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. 2020 Oct 1;11(5):1046–1057. doi: 10.14336/AD.2019.1025

Table 4.

Age associations with the LDL-C levels in each age phase adjusted for confounding factors.

Female Male
Independent variable Coef. 95% CI P Independent variable Coef. 95% CI P
Age phase I: 18 ≤ age ≤ 56 Age phase I: 18 ≤ age ≤ 33
Age 0.018 0.018~0.019 <0.001 Age 0.025 0.021~0.030 <0.001
Systolic BP / / / Systolic BP / / /
Diastolic BP 0.004 0.002~0.007 <0.001 Diastolic BP / / /
Glucose (mmol/L) 0.115 0.105~0.125 <0.001 Glucose (mmol/L) 0.169 0.153~0.186 <0.001
BMI (kg/m2) 0.041 0.032~0.050 <0.001 BMI (kg/m2) 0.071 0.055~0.087 <0.001
Inactive lifestyle 0.043 0.032~0.089 <0.001 Inactive lifestyle 0.021 0.011~0.067 <0.001
Moderate drinking / / / Moderate drinking 0.031 0.012~0.071 <0.001
Smoking / / / Smoking 0.075 0.061~0.079 0.002
Age phase II: 34 ≤ age ≤ 56
Age / / /
Systolic BP / / /
Diastolic BP 0.007 0.003~0.010 <0.001
Glucose (mmol/L) 0.030 0.022~0.037 <0.001
BMI (kg/m2) 0.035 0.023~0.048 <0.001
Inactive lifestyle 0.023 0.013~0.037 0.004
Moderate drinking 0.061 0.054~0.201 0.003
Smoking 0.103 0.108~0.232 0.001
Age phase II: age ≥ 57 Age phase III: age ≥ 57
Age -0.013 -0.016~-0.011 0.001 Age -0.008 -0.010~-0.005 <0.001
Systolic BP / / / Systolic BP / / /
Diastolic BP 0.012 0.007~0.018 <0.001 Diastolic BP 0.004 0.001~0.007 0.002
Glucose (mmol/L) 0.051 0.019~0.083) <0.001 Glucose (mmol/L) 0.038 0.026~0.050 <0.001
BMI (kg/m2) 0.024 0.010~0.038 0.002 BMI (kg/m2) 0.025 0.010~0.040 <0.001
Inactive lifestyle 0.021 0.016~0.037 0.007 Inactive lifestyle 0.034 0.020~0.043 0.004
Moderate drinking / / / Moderate drinking 0.043 0.032~0.077 0.009
Smoking / / / Smoking 0.023 0.016~0.052 0.008

For abbreviations, see Table 1 and 2. In each multivariate linear regression model, potentially independent variables according to the univariable analysis (p<0.10, see Table 2) were introduced into the starting model and then eliminated manually using the backward step-by-step approach, depending on the largestP value. "/" indicates that a variable is not significantly associated with LDL-C level in given model.