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Schedule of enrollment, intervention, and assessment. ADAS-Jcog = Alzheimer's Disease Assessment Scale-cognitive component-Japanese version, GDS = Geriatric depression scale, IADL = Instrumental Activity of Daily Life, MMSE = Mini Mental State Examination, NPI = Neuropsychiatric Inventory. ∗Vital sign: Blood pressure and pulse rate. †Blood tests: hematological examination and blood chemistry test.
