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Examples of responsive vs. non-responsive ICP to HTS. The pressure waveforms of responsive vs. non-responsive ICP to HTS. The shaded areas indicate the two 20-min windows with a 10-min delay used to evaluate the change due to HTS. AMP, amplitude pulse of ICP; CPP, cerebral perfusion pressure; HTS, hypertonic saline; ICP, intracranial pressure; MAP, mean arterial blood pressure; Mins/mins, minutes; mmHg, millimeters of mercury; PRx, pressure reactivity index
