Table 1.

Patient demographics and clinical characteristics with 15 different patients and 69 distinct bolus infusions of HTS

Characteristics	N (%) or median (interquartile range)
n (patients)	15
Age	35 (23–54)
Sex (male)	11 (73.3%)
Best GCS	7 (6–8)
Best GCS-motor	5 (4–5)
Pupillary light reflex
Bilateral reactive	9 (60%)
Unilateral unreactive	4 (26.6%)
Bilateral unreactive	2 (13.3%)
Pre-hospital hypoxia	10 (66.6%)
Pre-hospital hypotension	2 (13.3%)
CT-epidural hematoma	2 (13.3%)
Mean ISS	25 (25–27)
AIS-head/brain	5 (4.5–5)
Marshall classification category of 1st head-CT
III	4 (26.6%)
IV	6 (40%)
V	5 (33.3%)
Median GOSE outcome 1 month	4 (1–5)

Treatment was a 140-ml 7.5% hypertonic saline solution

AIS, abbreviated injury scale; CT, computed tomography; HTS, hypertonic saline; ISS, injury severity score; GCS, Glasgow coma score; GOSE, Glasgow Outcome Scale-Extended