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. 2020 Sep 21;15(9):e0239114. doi: 10.1371/journal.pone.0239114

Table 3. Diagnostic yield for multidisciplinary committee review of diagnoses by biopsy technique.

Conventional forceps Cryoprobe
N = 124 N = 124
GROUP 1. IIPs 12 (9.7%) 26 (21.0%)
OR (Cryo/Conv) 2.4762
[95% CI] [1.4543–4.2160]
P-value 0.0008
GROUP 2. ILD of known cause or association 4 (3.2%) 20 (16.1%)
OR (Cryo/Conv) 5.7692
[95% CI] [2.3269–14.3038]
P-value 0.0002
GROUP 3. Granulomatous ILD and miscellaneous ILD 5 (4.0%) 9 (7.3%)
OR (Cryo/Conv) 1.8626
[95% CI] [1.0127–3.4257]
P-value 0.0454
GROUP 4. Other non-ILD diagnoses 3 (2.4%) 4 (3.2%)
OR (Cryo/Conv) 1.3444
[95% CI] [0.7528–2.4009]
P-value 0.3171

OR, odds ratio; CI, confidence interval (upper and lower limits in square brackets); IIP, idiopathic interstitial pneumonia; ILD, interstitial lung disease.