Skip to main content
. 2020 Sep 21;15(9):e0239114. doi: 10.1371/journal.pone.0239114

Table 4. Multidisciplinary committee diagnoses by biopsy technique according to diffuse interstitial classification.

GROUP 1. Idiopathic interstitial pneumonias
Conventional Cryoprobe
N = 12 N = 26
Idiopathic pulmonary fibrosis 3 (2.4%) 10 (8.1%)
RB ILD-associated 4 (3.2%) 6 (4.8%)
Non-specific interstitial pneumonia 3 (2.4%) 5 (4.0%)
Organizing pneumonia 1 (0.8%) 4 (3.2%)
Desquamative interstitial pneumonia 1 (0.8%) 1 (0.8%)
GROUP 2. ILD of known cause or association
Conventional Cryoprobe
N = 4 N = 20
Hypersensitivity pneumonitis 3 (2.4%) 13 (10.5%)
Drug-induced pneumonitis 1 (0.8%) 3 (2.4%)
Lipoid pneumonia 0 2 (1.6%)
Connective tissue disease-associated ILD 0 2 (1.6%)
GROUP 3. Granulomatous ILD and miscellaneous ILD
Conventional Cryoprobe
N = 5 N = 9
Sarcoidosis 4 (3.2%) 6 (4.8%)
Pulmonary amyloidosis 1 (0.8%) 1 (0.8%)
Langerhans cell histiocytosis 0 1 (0.8%)
Lymphangioleiomyomatosis 0 1 (0.8%)
GROUP 4. Other non-ILD diagnoses
Conventional Cryoprobe
N = 3 N = 4
Lung neoplasm 3 (2.4%) 3 (2.4%)
Lymphoproliferative syndrome 0 1 (0.8%)

Data are presented as numbers and percentages. RB, respiratory bronchiolitis, IIP, idiopathic interstitial pneumonia; ILD, interstitial lung disease.