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. 2020 Sep 21;17(9):e1003318. doi: 10.1371/journal.pmed.1003318

Table 7. Comparative analysis of health outcomes.

ND
sd-mRDT-/us-qPCR-
LD parasitemia
sd-mRDT-/us-qPCR+
LD versus ND parasitemia
  Prevalence Crude bivariate analysis Adjusted (season)
Outcomes Mean 95% CI Mean 95% CI RRcrude 95% CI p-value RRadj 95% CI p-value
Days to fever clearance 3.5 (3.4–3.5) 3.2 (2.8–3.5) 0.9 (0.8 to −1.0) 0.2   0.9 (0.8–1.1) 0.4  
Admission duration (days) 5.1 (4.1–6.0) 3.0 (−22.4 to 28.4) 0.8 (0.4–1.6) 0.5   0.7 (0.3–1.5) 0.4  
  % Total = 2,527 % Total = 76   95% CI p-value RRadj CI95% p-value
Clinical failure 4.0 101 2.6 2 0.7 (0.2–2.6) 0.6   0.9 (0.2–3.5) 0.9  
Secondary hospitalization 2.8 72 2.6 2 0.9 (0.2–3.5) 0.9   1.0 (0.2–4.1) 0.9  
Death 0.3 8 0.0 0    

LD versus ND (low-density versus undetectable Pf parasitemia).

See S2 Table for the definition of clinical failure.

HD, high-density Pf infection; LD, low-density Pf infection; RR, risk ratio; RRadj, adjusted RR. sd-mRDT, standard malaria RDT; us-qPCR, quantitative PCR.