Table 7. Comparative analysis of health outcomes.
ND sd-mRDT-/us-qPCR- |
LD parasitemia sd-mRDT-/us-qPCR+ |
LD versus ND parasitemia | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Prevalence | Crude bivariate analysis | Adjusted (season) | ||||||||||
Outcomes | Mean | 95% CI | Mean | 95% CI | RRcrude | 95% CI | p-value | RRadj | 95% CI | p-value | ||
Days to fever clearance | 3.5 | (3.4–3.5) | 3.2 | (2.8–3.5) | 0.9 | (0.8 to −1.0) | 0.2 | 0.9 | (0.8–1.1) | 0.4 | ||
Admission duration (days) | 5.1 | (4.1–6.0) | 3.0 | (−22.4 to 28.4) | 0.8 | (0.4–1.6) | 0.5 | 0.7 | (0.3–1.5) | 0.4 | ||
% | Total = 2,527 | % | Total = 76 | 95% CI | p-value | RRadj | CI95% | p-value | ||||
Clinical failure | 4.0 | 101 | 2.6 | 2 | 0.7 | (0.2–2.6) | 0.6 | 0.9 | (0.2–3.5) | 0.9 | ||
Secondary hospitalization | 2.8 | 72 | 2.6 | 2 | 0.9 | (0.2–3.5) | 0.9 | 1.0 | (0.2–4.1) | 0.9 | ||
Death | 0.3 | 8 | 0.0 | 0 | – | – | – | – | – | – |
LD versus ND (low-density versus undetectable Pf parasitemia).
See S2 Table for the definition of clinical failure.
HD, high-density Pf infection; LD, low-density Pf infection; RR, risk ratio; RRadj, adjusted RR. sd-mRDT, standard malaria RDT; us-qPCR, quantitative PCR.