Table 1.
Demographic, Symptom, Arterial Blood Gas Test, and Routine Blood Test on Admission
| Moderate | Severe | Critical | |
|---|---|---|---|
| Number of patients | 25 | 47 | 27 |
| Age (y) (median, range) | 45 (24-67) | 53 (29-96) | 66 (36-90) |
| Mean ± SD | 46.6 ± 12.2 | 52.4 ± 14.3 | 65.6 ± 14.3 |
| Gender (M:F) | 12:13 | 28:19 | 18:9 |
| Symptom (count, %) | |||
| Illness days (mean ± SD, median) | 7.8 ± 5.8 (7) | 7.3 ± 4.0 (7) | 8.5 ± 3.9 (7) |
| Wu Han contact | 4 (16%) | 16 (34%) | 6 (22%) |
| Hypertension | 5 (20%) | 11 (23%) | 18 (67%) |
| Diabetes | 0 (0%) | 2 (4%) | 4 (15%) |
| History of surgery | 1 (4%) | 0 (0%) | 3 (11%) |
| Coronary heart disease | 0 (0%) | 3 (6%) | 2 (7%) |
| Hepatitis B | 2 (8%) | 1 (2%) | 1 (4%) |
| Fever | 21 (84%) | 38 (81%) | 23 (85%) |
| Chill | 1 (4%) | 4 (9%) | 3 (11%) |
| Cough and sputum | 16 (64%) | 29 (62%) | 17 (63%) |
| Dizziness and headache | 1 (4%) | 0 (0%) | 2 (7%) |
| Fatigue | 1 (4%) | 9 (19%) | 5 (19%) |
| Body aches | 4 (16%) | 7 (15%) | 2 (7%) |
| Chest tightness | 3 (12%) | 8 (17%) | 5 (19%) |
| Diarrhea | 0 (0%) | 3 (6%) | 4 (15%) |
| Routine blood test (mean ± SD, median) | |||
| White blood cell count | 6.3 ± 3.9 (5.1) | 7.2 ± 4.3 (6.0) | 9.3 ± 5.6 (7.8) |
| Lymphocyte percentage | 0.197 ± 0.115 (0.199) | 0.161 ± 0.112 (0.138) | 0.104 ± 0.069 (0.089) |
| Eosinophil ratio | 0.025 ± 0.070 (0.001) | 0.012 ± 0.052 (0.000) | 0.000 ± 0.001 (0.000) |
| Neutrophil | 4.8 ± 3.9 (3.4) | 5.9 ± 4.1 (4.4) | 8.1 ± 5.5 (7.2) |
| Lymphocyte count | 1.0 ± 0.5 (1.0) | 0.9 ± 0.5 (0.8) | 0.7 ± 0.4 (0.6) |
| Eosinophil count | 0.027 ± 0.073 (0.000) | 0.010 ± 0.030 (0.000) | 0.080 ± 0.382 (0.000) |
| C-reactive protein | 25.6 ± 35.3 (13.3) | 36.9 ± 38.0 (25.1) | 48.0 ± 40.6 (50.0) |
| Arterial blood gas test (mean ± SD, median) | |||
| Blood oxygen saturation | 96.9 ± 4.4 (98.2) | 96.1 ± 7.4 (97.8) | 95.9 ± 2.7 (96.3) |
| PO2 | 117.9 ± 38.9 (106.5) | 107.6 ± 40.9 (91.6) | 91.4 ± 37.8 (84.4) |
| PCO2 | 35.9 ± 3.2 (35.0) | 36.5 ± 4.4 (36.8) | 35.4 ± 5.2 (35.2) |
| PH | 7.4 ± 0.0 (7.4) | 7.4 ± 0.0 (7.4) | 7.4 ± 0.0 (7.4) |
| Activated partial prothrombin time | 31.7 ± 3.5 (31.3) | 32.2 ± 4.0 (31.9) | 32.8 ± 6.1 (33.6) |
| Prothrombin time | 12.2 ± 1.5 (12.1) | 11.9 ± 1.2 (11.7) | 11.9 ± 0.9 (11.8) |
| D-dimer | 403.3 ± 430.4 (281.0) | 553.6 ± 550.9 (380.0) | 2530.3 ± 9070.3 (608.0) |
| Lactate dehydrogenase | 244.0 ± 71.4 (223.0) | 267.0 ± 81.0 (246.0) | 341.7 ± 134.4 (330.0) |
| Phosphocreatine kinase | 97.6 ± 86.8 (60.0) | 96.8 ± 70.6 (70.0) | 143.1 ± 132.6 (97.0) |
| Creatine kinase isoenzyme | 22.1 ± 9.9 (19.0) | 18.8 ± 4.6 (20.0) | 22.7 ± 11.4 (22.0) |
| ALT | 38.5 ± 37.7 (26.0) | 29.1 ± 40.7 (20.0) | 25.2 ± 18.7 (19.0) |
| AST | 29.8 ± 24.4 (22.0) | 26.3 ± 18.0 (20.0) | 31.9 ± 28.6 (25.0) |
| Serum creatinine | 74.3 ± 22.9 (72.0) | 76.6 ± 13.5 (75.0) | 119.7 ± 183.8 (79.0) |
| Blood urea nitrogen | 5.0 ± 2.6 (4.5) | 5.8 ± 2.7 (5.2) | 7.9 ± 6.7 (5.6) |
| Procalcitonin | 0.09 ± 0.18 (0.05) | 0.08 ± 0.12 (0.06) | 0.23 ± 0.41 (0.07) |