Table 6.
Comparison of Model Performance With and Without CT Features for Prediction of Clinical Outcomes
| Clinical Outcomes | Selected features | Performance |
||
|---|---|---|---|---|
| With CT Features | Without CT Features | |||
| Duration of hospitalization (≤4 weeks) | %NLLV * (12) | CV RMSE | 0.878 | 0.916 |
| Age (11) | ||||
| Creatine_kinase_isoenzyme (7.9) | ||||
| Hypertension (6.9) | ||||
| PO2 (6.9) | ||||
| Duration of oxygen inhalation (≤4 weeks) | Age (15) | CV RMSE | 0.920 | 0.940 |
| %NLLV * (11) | ||||
| Creatine_kinase_isoenzyme (8.1) | ||||
| PO2 (7.6) | ||||
| Procalcitonin (6.7) | ||||
| Duration of sputum nucleic acid test positive (≤4 weeks) | Age (14) | CV RMSE | 0.901 | NA |
| History_of_surgery (7.8) | ||||
| Creatine_kinase_isoenzyme (7.0) | ||||
| Need of ICU | Age (23) | |||
| Procalcitonin (17) | AUC | 0.945 (0.941-0.948) | 0.932 (0.927-0.936) | |
| Hypertension (16) | Specificity | 0.843 | 0.845 | |
| %NLLV * (12) | Sensitivity | 0.884 | 0.879 | |
| C_reactive_protein (11) | Accuracy | 0.864 (0.858-0.870) | 0.862 (0.856-0.868) | |
| Duration of ICU (≤2 weeks) | HIST_var_lesion * (5.9) | CV RMSE | 0.688 | 0.798 |
| Blood_oxygen_saturation (5.3) | ||||
| Prediction of prognosis (partial recovery vs prolonged recovery) | Age (19) | |||
| %NLLV * (15) | AUC | 0.960 (0.957-0.963) | 0.806 (0.800-0.813) | |
| HIST_mad_residual * (12) | Specificity | 0.892 | 0.792 | |
| HIST_kurt_residual * (9.4) | Sensitivity | 0.907 | 0.659 | |
| HIST_quant_range_residual * (8.5) | Accuracy | 0.899 (0.895-0.904) | 0.726 (0.719-0.733) | |
Features with suffix “residual” are those for the nonlesion lung. CT features are marked with asterisks. Numbers in the parenthesis are the importance of the features, obtained from Boruta's selection process. For regression problems, the importance was evaluated based on the mean increase in MSE. For classification problems, it was based on the mean decrease in accuracy.