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. 2020 Sep 17;14:3777–3786. doi: 10.2147/DDDT.S270025

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© 2020 Ur Rehman et al.

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Effect of 4-FBS 20, 40, 60mg/kg p.o administration on the expression of nicotine-induced behavioral sensitization. BALB/c mice (n=6/group) were used in seven days protocol followed by a nicotine challenge dose on day 11. One-way ANOVA followed by Tukey’s test on day 11 showed that 4-FBS 40mg and 60mg have significant **p<0.01 ***p<0.001 reductions in locomotion as compared to nicotine. No significant difference was observed between saline and 4-FBS 20, 40 and, 60mg/kg on day 11.