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. 2020 Sep 17;14:3777–3786. doi: 10.2147/DDDT.S270025

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© 2020 Ur Rehman et al.

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Effect of nicotine sensitization and 4-FBS on Adenosine turnover in the striatum. BALB/c mice (n=6/group) striatum were used for this protocol. Adenosine levels were significantly increased (***p<0.001) in the nicotine group compared to the saline group. 4-FBS at the dose of 60mg/kg significantly reduces adenosine (*p<0.05). Other doses 20, 40, mg/kg) have no significant difference over nicotine treated group. One-way ANOVA followed by Tukey’s multiple comparison tests was used for this analysis.