Table 2.

Classification Metrics of tPSA, The PCA3 Score, The AMACR Score and Classification Models

	PCa Detection				csPCa Detection
	tPSA	PCA3 Score	AMACR Score	Model for PCa Detection	tPSA	PCA3 Score	AMACR Score	Model for csPCa Detection
Sensitivity	0.738	0.475	0.590	0.62	0.758	0.576	0.818	0.62
Specificity	0.552	0.806	0.701	0.79	0.474	0.768	0.547	0.81
AUC, 95%CI	0.643 (0.547–0.739)	0.664 (0.570–0.758)	0.666 (0.571–0.760)	0.77 (0.63–0.86)	0.612 (0.495–0.729)	0.632 (0.511–0.752)	0.711 (0.617–0.806)	0.72 (0.58–0.83)
Optimal cutoff	7.41	76.64	61.57	0.52	7.41	78.61	52.19	0.52