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EC50 values (95% confidence intervals) (pM) of DES and E2 as derived from the data presented in Fig. 2
| Assay | EC50 E2 (pM) | EC50 DES (pM) |
|---|---|---|
| U2OS-ERα reporter gene expression | 2.5 (2.3–2.9) | 8.4 (7–9.9) |
| T47D cell proliferation | 7.5 (5.3–10.6) | 16.6 (11.9–23.3) |
