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. 2020 Sep 8;11:621. doi: 10.3389/fendo.2020.00621

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Copyright © 2020 Sun, Jiao, Han, Zhang, Shi, Shi and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Mendelian randomization (MR) association of serum metabolites on the risk of polycystic ovary syndrome (PCOS). Causal estimates are obtained using metabolite-related single-nucleotide polymorphisms (SNPs) as instrumental variables using the inverse variance weighted (IVW) method. Odds ratio (OR) and 95% confidence intervals (95% CIs) are provided for PCOS per 1-s.d. higher level of specific metabolite.