TABLE 1.

Epigenetic changes depression: related gene and expression.

Depression	DNA methylation site	Gene expression/affect	References
CUMS	− 681 CpG	5-HT1A	Le François et al., 2015; Zurawek et al., 2019
	− 694 to −105 CpG	CRMP2	Li W. et al., 2020; Xiang et al., 2020
	− 863 to −732 CpG	Tacr2	Micale et al., 2008; Xiang et al., 2019
ELS	Hypothalamic neurons CpG	NR3C1	Bockmühl et al., 2015; Holmes et al., 2019
	chromosome 6p21.31	FKBP5	Harms et al., 2017; Tozzi et al., 2018
	CRCh37/hg19	MORC1	Nieratschker et al., 2014; Thomas et al., 2020
PD	HSD11B2	cortisol	Appleton et al., 2015; Seth et al., 2015
	−?934 CpG	OXTR	Maud et al., 2018; Tops et al., 2019
	Chromosome 3	AVP	King et al., 2017; Solomonova et al., 2019
PPD	8810078 and 8810069 CpG	Antenatal serum estradiol	Kimmel et al., 2016; Osborne et al., 2016
	− 22 to −23 CpG	NR3C1	Oberlander et al., 2008; Murgatroyd et al., 2015