FIGURE 1.

An illustration of nonfluorescent bioassay using bio–barcoded nanowires. (A) DNA strands labeled A–C are likely to be not complementary to the respective primed counterparts (A′–C′). The strands double prime (″) labeled are likely to link the respective sequences to their primed counterparts through complementary DNA hybridization. (B) The striped particles are derivatized using capture antibody (a), analyte (b), and the fluorescent labeled detection antibody addition (c). (C) The striped particles are derivatized through NeutrAvidin (NA), a biotinylated capture sequence’s reaction (a), a special phase analyte (b), and fluorescent labeled oligonucleotides for detection (c).