TABLE 2.

Effect of (pyr)apelin-13 on open field test in mice.

Treatment	Dose (mg/kg)	n	Total distance traveled (mm)	Average velocity (mm/s)	Spontaneous activity (n)
Vehicle	–	11	15939.11 ± 2229.23	8.85 ± 1.24	281.18 ± 13.80
(pyr)Apelin-13	2	10	16044.83 ± 4131.48	8.91 ± 2.30	245.40 ± 21.63
(pyr)Apelin-13	10	9	12940.84 ± 1762.58	7.19 ± 0.98	259.33 ± 19.98
(pyr)Apelin-13	20	10	14557.33 ± 3818.45	8.09 ± 2.12	248.00 ± 26.40

ANOVA was used to compare the difference between (pyr)apelin-13 and vehicle.