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Effect of (pyr)apelin-13 in the light/dark aversion test in mice.
| Treatment | Dose (mg/kg) | n | Number of transitions/5 min | Time (s) lit area/5 min |
| Vehicle | – | 10 | 8.90 ± 3.41 | 244.20 ± 23.85 |
| (pyr)Apelin-13 | 2 | 9 | 10.44 ± 3.79 | 233.00 ± 22.52 |
| (pyr)Apelin-13 | 10 | 9 | 12.00 ± 2.12 | 224.67 ± 18.25 |
| (pyr)Apelin-13 | 20 | 9 | 8.00 ± 3.34 | 267.33 ± 15.29 |
ANOVA was used to compare the difference between (pyr)apelin-13 and vehicle.
