TABLE 2.

The clinical role of SIRT2 in five malignancies.

Malignance	Method of study	Role of SIRT2	References
Breast cancer	IHC IHC	Tumor suppressor Tumor suppressor	Kim et al. (19) Shi et al. (49)
	qPCR IHC	Tumor suppressor Oncogene (nuclear expression)	McGlynn et al. (50)
Hepatocellular carcinoma	Microarray qPCR, IHC IHC, database	Tumor suppressor Oncogene Oncogene	Kim et al. (19) Chen et al. (51) Huang et al. (52)
NSCLC	qPCR, WB, IHC IHC	Tumor suppressor Oncogene	Li et al. (54) Grbesa et al. (57)
Colorectal cancer	IHC WB, database	Tumor suppressor Oncogene	Zhang et al. (63) Hu et al. (67)
Glioma	qPCR, WB Northern blot	Tumor suppressor Tumor suppressor	Li et al. (70) Hiratsuka et al. (69)
	IHC	Oncogene (nuclear expression)	Imaoka et al. (73)