Table 2.
Microbiota changes in inflammatory bowel syndrome patients
| First author [Ref.], year | Study group | Samples | Phyla | Genus/species |
|---|---|---|---|---|
| Fuentes [75], 2017 | 29 UC/15 healthy controls | rectum biopsies | ↑ Bacteroidetes | ↑ Clostridium cluster XIVa ↓ Bacteroides fragilis and vulgatus |
| Ramakrishna [76], 2015 | 32 UC/28 CD/30 healthy controls | mucosal biopsies | ↓ Firmicutes/Bacteroidetes ratio | UC: ↑ Bacteroides ↑ Lactobacillus ↑ Escherichia coli CD: ↓ Clostridium coccoides |
| Rajca [71], 2014 | 33 CD/29 healthy controls | stool | ↓ Firmicutes | ↑ Escherichia coli
↓ Clostridium coccoides and leptum ↓ Faecalibacterium prausnitzii |
| Wang [72], 2014 | stool: 21 CD/34 UC/21 healthy controls mucosa-associated samples: 15 CD/29 UC/ 21 healthy control |
stool and mucosa-associated samples | IBD: ↓ Faecalibacterium prausnitzii UC: ↑ Bifidobacterium CD: ↑ Lactobacillus |
|
IBD, inflammatory bowel disease; CD, Crohn's disease; UC, ulcerative colitis.