Table 1.

Course, dose, and success of drug therapy

Initiation of therapy	Therapy	Dose, mg	Therapeutic effect
2010	Pregabalin Amitriptyline	150-0-300 0-0-75	NRS 5/10
April 2014 (first presentation)	Pregabalin Amitriptyline Duloxetine	300-0-300 0-0-75 30-0-0	Discontinued by patient due to intolerance
May 2014	Pregabalin Amitriptyline Tapentadol	300-0-300 0-0-75 50-0-50, increased from the third day on 100-0-100	NRS 5/10 Initiation of therapy due to severe pain
July 2014	Pregabalin Amitriptyline Tapentadol	150-0-150 0-0-75 150-0-150	Dose increase due to persistent pain
September 2014 (begin capsaicin 8%)	Capsaicin 8% Pregabalin Amitriptyline Tapentadol	1 patch; 30 min 150-0-150 0-0-50 150-0-150	NRS 3–4/10 Hyperesthesia ↓ Allodynia ↓↓↓
Since August 2015	Capsaicin 8% Pregabalin Amitriptyline Tapentadol	1-2 patches; 30 min; every third month, 18 treatments in total 150-0-150 0-0-50 150-0-150