Figure 2.
Plasma levels of tryptophan, kynurenine and KYNA in pre-pubertal (PD21), adolescent (PD 32 – 35), and adult (PD 56 – 85) offspring are not altered by prenatal exposure to kynurenine (EKyn). (A) Plasma tryptophan: no significant three-way age x sex x prenatal condition interaction; significant main effect of age and sex, but not prenatal treatment. (B) Plasma kynurenine: no significant three-way age x sex x prenatal condition interaction; significant main effect of age, but not sex or prenatal treatment. (C) Plasma KYNA: no significant three-way age x sex x prenatal condition interaction; significant main effect of age, but not sex or prenatal treatment. All data are mean ± SEM. N = 6 – 12 litters per group.