Table 2.
The top 10 differentially expressed genes (DEGs) between older women with osteoporosis and vertebral fracture (VF) and osteoporosis with no vertebral fractures (NVFs)
| Genes | Symbol | (β) | Regulated | p‐value |
|---|---|---|---|---|
| Syntrophin gamma 2 | SNTG2 | 31.88 | Up | .004 |
| Prader‐Willi region nonprotein coding RNA 1 | PWRN1 | 17.6 | Up | .006 |
| Keratin‐Associated Protein 19‐1 | KRTAP19‐1 | 15.31 | Up | .008 |
| Lipocalin 1 | LCN1 | 14.89 | Up | .006 |
| Ectonucleotide Pyrophosphatase/Phosphodiesterase 2 | ENPP2 | 13.45 | Up | .007 |
| Cysteine Rich Tail 1 | CYSRT1 | 12.91 | Up | .009 |
| CD248 Molecule | CD248 | 12.64 | Up | .004 |
| TRAF3 Interacting Protein 2 | TRAF3IP2 | 12.18 | Up | .006 |
| Partner Of NOB1 Homolog | PNO1 | 11.66 | Up | .007 |
| Glycoprotein V Platelet | GP5 | 11.09 | Up | .008 |
| Rho GTPase activating protein 8 | ARHGAP8/PRR5‐ARHGAP8 | −19.35 | Down | .005 |
| MTOR‐associated protein, LST8 homolog | MLST8 | −14.8 | Down | .008 |
| Phospholipid Transfer Protein | PLTP | −14.73 | Down | .008 |
| Synapse defective 1, Rho GTPase, homolog 1 (C. elegans) | SYDE1 | −14.41 | Down | .009 |
| Glycosylphosphatidylinositol‐Specific Phospholipase D1 | GPLD1 | −13.96 | Down | .009 |
| Zinc Finger Protein 653 | ZNF653 | −12.91 | Down | .003 |
| Deleted In Primary Ciliary Dyskinesia Homolog | DPCD | −12.45 | Down | .004 |
| Serine/Threonine Kinase 16 | STK16 | −12.39 | Down | .006 |
| Alpha‐1,4‐N‐Acetylglucosaminyltransferase | A4GNT | −11.35 | Down | .006 |
| ECSIT Signaling Integrator | ECSIT | −9.52 | Down | .007 |