Table 1.

Recipients, indications for transplantation, conditioning, and cell dose

Age/sex	CGD type	Clinical disease	Manifestations of CGD present at transplant/pretransplant CRP (mg/L) and immunosuppression	Busulfan AUC min × microm/L	TNC (109)	Cd 34+ cells/kg (106)	CD3+ cells/kg (107)
14/M	XL (p91-phox)	Infection/protein-losing enteropathy, colitis	Protein-losing enteropathy and Nocardia pneumonia/2.90, prednisone 7.5 mg daily and mesalamine DR 400 mg every 8 h	2461	31.5	7.98	16.89
26/F	P67 (NCF-2)	Infection	A. nidulans pneumonia and osteomyelitis/17.10, none	3610	92.4	9.24	9.31
24/M	P47 (NCF-1)	Infection, colitis, and dermatitis	Colitis and dermatitis/5.00, prednisone 20 mg daily, and mesalamine DR, 1200 mg twice daily	3828	50.3	9.84	21.5
16/M	XL (p91-phox)	Infection, colitis, cystitis, recurrent fever, and headaches	Colitis, bladder disease/12.60, prednisolone 5 mg twice daily	3619	91.0	15.9	20.5
14/M	XL (p91-phox)	Infection and colitis	S. apiospermum pneumonia and pericarditis, Colitis/5.90, prednisone 5 mg daily, and sulfasalazine 500 mg daily	3008	27.6	12	14.9
22/F	XL (p91-phox) carrier	Infection (Nocardia), colitis	Colitis and discoid lupus/5.40, azathioprine 150 mg daily, mesalamine 1.2 g every 12 h, prednisone 15 mg daily, and hydroxychloroquine 200 mg daily	3349	105	10.5	14.1
19/M	XL (p91-phox)	Infection and colitis	Colitis/6.60, mesalamine DR 1200 mg twice daily, and prednisone 7.5 mg twice daily	4250	55.2	9.85	12.32

CGD chronic granulomatous disease, CRP high-sensitivity comprehensive C-reactive protein, AUC area under the curve, TNC total nucleated cell dose, XL X-linked, DR delayed release: A. nidulans, Aspergillus nidulans; S. apiospermum, and Scedosporium apiospermum