Table 2.

Transplant donor, engraftment, complications, and outcome

Age/sex	Donor (age), HLA match, and ABO compatible	Engraftment day/granulocyte transfusion days	Myeloid/CD3+ cell chimerism	aGVHD grades/cGVHD severity	Viral reactivation/intervention	Post-transplant infections	Follow-up or cause of death/interval
14/M	Father (33), 8/10, yes	PMN 15, platelets 14/5 and 11	100/≥ 97% from first assessment	Grade 2 acute GI/no	EBV/none Grade 2 HC with BK viruria	C. difficile-associated diarrhea	Resolved Nocardia pneumonia 18 months, persistent PLE, cure/> 3 years
26/F	Mother (45), 10/10, yes	PMN 21, platelets 23/9, 10, 12, 13, and 14	100/≥ 98% from first assessment	Grade 2 acute GI, grade 1 skin/no	CMV/preemption EBV/none	S. aureus sternal wound infection	Aspergillus infection resolved 11 months, Cure/> 3 years
24/M	Brother (18), 8/10, yes	PMN 17, platelets 31	100/100% at all points	Grade 2 acute skin and grade 1 GI/yes, mild-limited	EBV/none Grade 1 HC with BK viruria	C. difficile-associated diarrhea	Cure > 3 years
16/M	Father (43), 5/10, yes	PMN 12, platelets 19	100/100% at all points	Grade 3 skin, GI/ mild	CMV/preemption EBV/none Grade III HC with BK viruria	A. fumigatus pneumonia E. coli bacteremia B. fragilis bacteremia	Cure > 2 years
14/M	Father (34), 6/10, yes	PMN 24, platelets 17/9, 21	100/100% at all points	Grade 2 GI	EBV/none CMV colitis/treatment	S. mitis bacteremia	Resolved fungal pneumonia/pericarditis 12 months, cure > 4 years
22/F	Father (53), 5/10, yes	PMN 20, Platelets 29	96–100%, 98–100%	Steroid-refractory GI	EBV/none Disseminated adenovirus	K. pneumoniae/E.coli pneumonia	Death day 131
19/M	Father (52), 3/6, yes	PMN 22, platelets 107	100/100% At all points	Liver steroid- refractory GI	EBV PTLD/rituximab CMV/preemption Grade III HC with BK viruria	E. faecium bacteremia Nocardia/Enterobacter pneumonia Rhizopus sp. pneumonia	Death day 316

HLA human leukocyte antigen, PMN polymorphonuclear leukocytes, aGVHD acute graft-versus-host disease, cGVHD chronic graft-versus-host disease, GI gastrointestinal, EBV Epstein-Barr virus, CMV cytomegalovirus, PTLD post-transplant lymphoproliferative disease, HC hemorrhagic cystitis,C. difficile Clostridioides difficile, S. aureus Staphylococcus aureus, A. fumigatus, Aspergillus fumigatus, E. coli Escherichia coli, B. fragilis Bacteroides fragilis, S. mitis Streptococcus mitis, K. pneumoniae Klebsiella pneumoniae, E. faecium Enterococcus faecium, PLE protein-losing enteropathy