Figure 1.
GLP-1 receptor agonist alleviated body weight, liver index and glucose homeostasis in rats. A) Body weight; B) liver index; C) intraperitoneal glucose tolerance test (IPGTT); D) area under curve of glucose; E) euglycemic hyperinsulinemic clamp test in three groups (n=6 per group) after 4-week drug administration. Results are expressed as the mean ± SD.*P<0.05 vs ND; #P<0.05 vs HFD. ND, normal diet; HFD, high fructose diet; HFD+Ex, high fructose diet group with exenatid intervention; AUCglu, area under the curve; GIR, glucose infusion rate.