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. 2020 Sep 15;64(3):3160. doi: 10.4081/ejh.2020.3160

Figure 4.

Figure 4.

GLP-1 receptor agonist alleviated high-fructose-induced de novo lipogenesis in rats. A) The relative mRNA expression level of SREBP-1 in three groups (n=6 per group) after 4-week drug administration. B) The relative mRNA expression levels of ACC, FAS and SCD-1 in the lipogenic pathway. C) SREBP-1 protein expression was determined by western blotting (n=6 per group); β-actin served as the loading control. D) Protein expression levels of ACC, FAS and SCD-1. Results are expressed as the mean ± SD. *P<0.05 vs ND, #P<0.05 vs HFD; SREBP-1, sterol regulatory element-binding protein 1; ACC, acetyl-CoA carboxylase; FAS, fatty acid synthase; SCD-1, stearoyl-CoA desaturase 1.