FIGURE 1.

Methods of DIXON, EPG‐T2 and DWI explained. A schematic representation of the water‐fat partial volume effect in each of the used acquisition methods. Situation 1 (top row) represents a voxel with low fat infiltration and situation 2 (bottom row) one with high fat infiltration. The pink quadrant in the first column represents muscle tissue, which is assumed to contain only water. The yellow quadrant represents fat tissue, which is assumed to contain ~10% of water that is rendered dark yellow. The DIXON method distinguishes between water and fat, and slightly underestimates the fat quantity because of attributing its water content to the water/muscle compartment. EPG‐T2 uses a two‐compartment fit accounting for the fat compartment. However, the estimated T2 of the water compartment is a combination of water in muscle and water in fat. The diffusion‐weighted imaging (DWI) acquisition has fat suppression and therefore only measures the water signal. Therefore, the measured diffusion properties are a combination of water in muscle and water in fat