TABLE 3.

Descriptive statistics of the dataset. Cross‐sectional statistics of differences in qMRI outcomes between the SMA and control cohort. All reported values are in mean ± standard deviation

QMRI	SMA	CONTROLS
FF‐DIXON (%)	47.6 ± 17.4	7.6 ± 1.5	mean difference: −40.0; 95% CI [−47.0 to −33.0] standardized mean difference: 3.06; P‐value <0.001
T2 (ms)	27.3 ± 1.5	28.9 ± 0.4	mean difference: 1.54; 95% CI [0.9 to 2.2] standardized mean difference: −1.38; P‐value <0.001
DTI ‐ FA	0.41 ± 0.09	0.24 ± 0.03	mean difference: −0.17; 95% CI [−0.2 to −0.1] standardized mean difference: 2.41; P‐value <0.001
DTI – MD (mm2/s)	1.13 ± 0.28	1.47 ± 0.10	mean difference: 0.34; 95% CI [0.2 to 0.5] standardized mean difference: −1.54; P‐value <0.001

Abbreviations: CI, confidence interval; DTI, diffusion tensor imaging; FA, fractional anisotropy; FF, fat fraction; MD, mean diffusivity; qMRI, quantitative magnetic resonance imaging; SMA, spinal muscular atrophy. Standardized mean difference according to Hedge's g.