FIGURE 3.

Effect of EPO on LPS‐induced leukocyte infiltration in placenta. Placentae were collected. Total density of leukocytes in placenta was assessed at 12 hours after the first LPS or vehicle solution injection on GD15. Total density of leukocytes in placenta was determined by hematoxylin and eosin. Representative photomicrographs of placental histological specimens from mice treated with normol saline + normol saline (A as control), normal saline + EPO (B), normal saline + LPS (C), and EPO + LPS (D) are shown. (C) shows prominent leukocyte infiltration in placenta (black arrows). In (A), (B) and (D), the infiltration of leukocytes is barely visible. Original magnification, ×100 or 400. Scale bars 100 µm for original magnification, ×100. Scale bars 20 µm for original magnification, ×400