Figure EV3. The knockdown of AURKB alters IPF‐specific gene network.

• A
  Primary lung‐resident fibroblasts isolated from TGFα mice on Dox for 10 days. Cells were transiently transfected with control or Aurkb siRNA, and transcripts were quantified by RT–PCR after 72 h. Data were presented as mean ± SEM. ****P < 0.00005, unpaired t‐test (n = 3).
• B
  Heat map shows two clusters of differentially expressed genes up‐ or downregulated (indicated with color key) by twofold or more upon genetic knockdown of Aurkb compared to control siRNA. (n = 3).

Data information: All data were presented as mean ± SEM.