TABLE 3.
Univariate analyses of demographic, inflammatory markers, and physiologic related to behavioral symptoms as measured using the HAMD, HAM‐A, and MMSE
| Variable | Univariate analysis | |||||
|---|---|---|---|---|---|---|
| Depression | Anxiety | Cognition | ||||
| r | p | r | p | r | p | |
| Age | 0.21 | .08 | 0.08 | .53 | 0.00 | .99 |
| BMI | 0.02 | .88 | −0.15 | .21 | 0.37 | .12 |
| Time | −0.05 | .67 | −0.11 | .35 | −0.06 | .60 |
| Tumor area | −0.22 | .07 | −0.22 | .66 | −0.03 | .84 |
| Edema area | 0.04 | .72 | 0.14 | .24 | −0.08 | .49 |
| HAMD | — | — | 0.45 | .00** | −0.08 | .51 |
| HAM‐A | 0.45 | .00** | — | — | −0.08 | .51 |
| MMSE | −0.08 | .51 | −0.08 | .51 | — | — |
| TNF‐α | −0.12 | .31 | −0.34 | .08 | 0.43 | .00** |
| IL−1α | −0.02 | .90 | −0.25 | .04* | −0.06 | .61 |
| IL−2 | −0.18 | .14 | −0.35 | .00** | 0.56 | .00** |
| IL−6 | 0.08 | .52 | 0.03 | .84 | −0.16 | .18 |
| IL−8 | −0.05 | .66 | −0.15 | .21 | 0.38 | .00** |
| IL−10 | −0.07 | .57 | −0.07 | .57 | −0.12 | .34 |
| CRP | 0.30 | .01** | 0.22 | .07 | −0.51 | .00** |
| GDNF | −0.09 | .49 | −0.25 | .04* | 0.32 | .01** |
| IFN‐γ | 0.40 | .00** | 0.19 | .12 | −0.06 | .63 |
| t | p | t | p | t | p | |
|---|---|---|---|---|---|---|
| Gender | −1.15 | .25 | 0.43 | .69 | −1.49 | .14 |
| Grade | −0.16 | .84 | −1.15 | .25 | −0.35 | .73 |
| Epilepsy | −0.27 | .79 | −1.21 | .24 | −0.75 | .46 |
| KPS | −1.47 | .16 | −5.64 | .00* | −1.00 | .32 |
| Marrige status | 3.43 | .00* | 1.71 | .09 | 1.47 | .16 |
| F | p # | F | p # | F | p # | |
|---|---|---|---|---|---|---|
| Lobe | 1.94 | .15 | 2.75 | .07 | 0.67 | .51 |
| Laterality | 0.73 | .49 | 1.86 | .16 | 0.43 | .65 |
| Education | 0.96 | .39 | 1.35 | .27 | 3.17 | .05 |
| Income | 2.84 | .07 | 3.62 | .03 | 0.85 | .43 |
p #: p value passes through Bonferroni correction.
*difference is statistically significant.
**difference is highly statistically significant.