Table 2.

Overview of Hippo signalling pathway induced lncRNAs in cancer development

LncRNA	Tumour type	Expression	Interaction with Hippo cascade	Biological function in cancers	Ref.
BCAR4	BC	↑	YAP promotes BCAR4 expression	Glycolysis	26
CYTOR (LINC00152)	CRC	↑	YAP increases CYTOR expression, which in turn sponges to miR‐632 and miR‐185‐3p to target FSCN1	Proliferation, invasion, metastasis	51
H19	Osteosarcoma, bladder cancer	↑	YAP increases H19 expression	Proliferation, migration	53, 90
MT1DP	Liver cancer	↓	YAP and Runx2 inhibit MT1DP expression dependent on FoxA1	Proliferation, apoptosis, colony formation	47
NORAD	Lung and breast cancer metastasis	↓	YAP/TAZ‐TEAD and NuRD complex repress NORAD expression	Migration and invasion	52

Abbreviations: ↑ upregulated; ↓ downregulated; BC, breast cancer; BCAR4, breast cancer antiestrogen resistance 4; CRC, colorectal cancer; CYTOR, cytoskeleton regulator RNA; FSCN1, fascin actin‐binding protein 1; MT1DP, metallothionein 1D, pseudogene; NORAD, non‐coding RNA activated by DNA damage; TAZ, transcriptional co‐activator with PDZ‐binding motif; TEAD, transcriptional enhancer‐associated domain; YAP, yes‐associated protein.