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. 2020 Aug 5;10(9):e01777. doi: 10.1002/brb3.1777

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© 2020 The Authors. Brain and Behavior published by Wiley Periodicals LLC

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Effects of estrogen on the mNSS in each group. (a) mNSS in each group 1 day after the injury; (b) mNSS in each group 3 days after the injury; (c) mNSS in each group 7 days after the injury; (d) mNSS in each group 14 days after the injury; *p < .05 indicated compared with the Sham group; ^# p < .05 indicated compared with the normal estrogen group. mNSS, modified neurological severity score. The rats in the Sham group received sham operation of scalp incision as a negative control; in all the other four groups, the rats were received a subcortical axonal fiber injury surgery as the test groups