Figure 7.

Effects of estrogen on the expression of p‐Akt, CDK5, p‐Ser262, p‐Ser404, and p‐Thr205 in each group. (a) Western blotting results of p‐Akt, CDK5, p‐Ser404, p‐Thr205, and p‐Ser262; (b) The relative optical density (OD) of p‐Akt/T‐Akt, CDK5, p‐Ser404, p‐Thr205, and p‐Ser262, respectively; *p < .05 indicated compared with the Sham group, ^# p < .05 indicated compared with the normal estrogen group; LY, LY294002. The rats in the Sham group received sham operation of scalp incision as a negative control; in all the other four groups, the rats were received a subcortical axonal fiber injury surgery as the test groups