TABLE 1.
Demographic characteristics of the cohort by dementia status
| Characteristic N (%) | Total N = 246 | Cognitively stable N = 91 (37%) | Demented N = 155 (63%) |
|---|---|---|---|
| Age at first visit: Mean years (S.D.) | 46.7 (5.2) | 45.5 (4.8) | 47.3 (5.3)* |
| Sex: N (%) | |||
| Male | 151 (61.4) | 54 (35.8) | 97 (64.2) |
| Female | 95 (38.6) | 37 (38.9) | 58 (61.1) |
| Level of intellectual disability N (%) | |||
| Mild/moderate | 150 (61.0) | 55 (60.4) | 95 (61.3) |
| Severe/profound | 96 (39.0) | 36 (39.6) | 60 (38.7) |
| Apolipoprotein genotypes: N (%) | N = 184 | N = 58 | N = 126 |
| APOE ε4 allele | 38 (20.7) | 9 (15.5) | 29 (23.0) |
| APOE ε2 allele | 30 (16.3) | 9 (15.5) | 21(16.7) |
| Hypothyroidism: N (%) | 139 (57.2) | 47 (52.8) | 92 (59.7) |
| High cholesterol: N (%) | 75 (30.5) | 29 (31.6) | 46 (29.7) |
| BMI (SD) | 30.2 (6.6) | 30.8 (6.6) | 30.2 (6.3) |
| Diabetes: N (%) | 8 (3.3) | 5 (5.5) | 3 (1.9) |
* P < .05
Abbreviations: APOE, apolipoprotein E; BMI, body mass index; SD, standard deviation.