Table L.4.
Sum PFASs serum levels at age 5 vs. tetanus antibody titres (log 2) at age 7
| Decile | Sum_PFAS (ng/mL) | N | Mean | SE | SD | t‐test | %change | |
|---|---|---|---|---|---|---|---|---|
| p | ||||||||
| 1 | 14.7 | 43 | 1.225 | 0.282 | 1.85 | Referent | No NOAEC for deciles | |
| 2 | 17.5 | 43 | 1.343 | 0.335 | 2.20 | 0.79 | 9 | |
| 3 | 19.5 | 43 | 1.205 | 0.287 | 1.88 | 0.96 | –1 | |
| 4 | 20.8 | 43 | 0.534 | 0.293 | 1.92 | 0.09 | –38 | NOAEC identified in quintile below |
| 5 | 22.5 | 43 | 1.232 | 0.263 | 1.72 | 0.99 | 0 | |
| 6 | 24.2 | 43 | 1.163 | 0.32 | 2.10 | 0.88 | –4 | |
| 7 | 25.8 | 43 | 0.852 | 0.321 | 2.10 | 0.47 | –23 | |
| 8 | 28.2 | 43 | 0.608 | 0.317 | 2.08 | 0.19 | –35 | |
| 9 | 31.2 | 43 | 0.51 | 0.321 | 2.10 | 0.10 | –39 | |
| 10 | 38.5 | 43 | 0.57 | 0.372 | 2.44 | 0.16 | –36 | |
| Quintiles | Sum_PFAS | N | Mean | SD | t‐test | %change | ||
| p | ||||||||
| 1 | 16.1 | 86 | 1.28 | 2.03 | Referent | |||
| 2 | 20.2 | 86 | 0.87 | 1.90 | 0.17 | –25 | ||
| 3 | 23.4 | 86 | 1.20 | 1.92 | 0.79 | –6 | ||
| 4 | 27.0 | 86 | 0.73 | 2.09 | 0.08 | –32 | ||
| 5 | 34.8 | 86 | 0.54 | 2.28 | 0.03 | –40 |
Yellow highlighted text = NOAEC; Blue highlighted text = LOAEC.
Total number of individuals in these analyses = 431. Divided into deciles: ~ 43 and quintiles ~ 86. Mean and standard error provided on log‐2 scale SD derived. p‐value: t‐test (assuming log‐normal distribution). % change estimated based on mean difference relative to the lowest (referent) decile corresponds to % shift on median concentration on the original (back‐transformed scale). Mean and SD pooled (from deciles) to estimate NOAEC in quintiles.