Table M.1a.

Ratios of concentrations in breast milk and maternal serum of PFOA, PFNA, PFHxS and PFOS, calculated based on mean or median values reported by various authors

Reference	Milk/serum ratio
	Based on mean values				Based on median values
	PFHxS	PFOS	PFOA	PFNA	PFHxS	PFOS	PFOA	PFNA
Kärrman et al. (2007)	0.018	0.0097	NA	NA	0.018	0.0089	NA	NA
Haug et al. (2011a,b)	NA	0.014	0.038	NA	NA	0.013	0.018	NA
Kim et al. (2011a)	0.006	0.009	0.018	NA	0.018	0.011	0.025	NA
Liu et al. (2011)	NA	0.018	0.11	0.047	NA	0.014	0.096	0.039
Median	0.012	0.012	0.038	0.047	0.018	0.012	0.025	0.039

NA: not applicable.

Note: Median ratios were the basis for the values used in the PBPK modelling, being 0.015 for PFHxS/PFOS and 0.03 for PFOA/PFNA.