Table N.1.
Search terms
| Human observations | |
|---|---|
|
Search terms Dates |
perfluoro* OR pfos OR pfoa OR pfas OR ‘fluorotelomer alcohol’ AND ‘human health’ OR ‘adverse effect*’ OR ‘occupational case*’ OR occupational OR epidemiol* OR biomarker OR ‘biological marker’ OR poison* OR ‘incidental poison*’ OR ‘case stud*’ OR adverse OR ‘case control*’ OR ‘case report*’ OR human OR adult OR man OR woman OR men OR women OR female OR male OR child OR children OR infant OR neonate OR maternal OR cohort OR prenatal 01 January 2013–31 Dec 2017. Extended to 01 August 2019 for studies on blood lipids, liver/ALT, birthweight, immune outcomes, carcinogenicity and endocrine effects (other than those under thyroid function & disease) |
| Toxicity | |
| Search terms Dates | perfluoro* OR pfos OR pfoa OR pfas OR ‘fluorotelomer alcohol’ AND toxicity OR toxi* OR acute OR subacute OR subchronic OR chronic OR mutagen* OR carcino* OR cardiotox* OR genotox* OR reprotox* OR nephrotox* OR neurotox* OR hepatotox* OR immune OR immuno* OR hematotox* OR haematotox* OR cytotox* OR ‘developmental tox*’ OR thyroid OR endocri* OR endocrine OR estrogen OR oestrogen OR fertility OR tumour OR tumor OR gestat* OR lactat* OR ‘DNA damage’ OR mortality OR adverse OR ‘adverse effect’ OR ‘blood lipid*’ OR ‘serum lipid*’ OR PPAR OR ‘ex vivo’ OR ‘in vitro’ OR ‘in vivo’ OR exvivo OR invitro OR invivo OR cell* OR tissue* OR rodent* OR mouse OR animal* OR rat* OR mice OR rabbit* OR dog* OR monkey* OR ‘experimental animal*’ OR ‘lab* animal*’ 01 January 2013–16 August 2019 |
| Toxicokinetics | |
| Search terms Dates | perfluoro* OR pfos OR pfoa OR pfas OR ‘fluorotelomer alcohol’ AND toxicokinetic* OR absorption OR distribution OR metabolism OR excretion OR ADME OR biotransformation OR pharmacokinetic* OR disposition OR fate OR transfer OR conjugat* OR hydroxylation OR ‘half‐life’ OR ‘half life’ OR PBPK OR ‘physiologically based pharmacokinetic modelling*’ OR uptake OR elimination OR urine OR bile OR faeces OR feces OR milk 01 January 2013–16 August 2019 |
| Biomonitoring | |
| Search terms Dates |
perfluoro* OR pfos OR pfoa OR pfas OR ‘fluorotelomer alcohol’ AND teeth OR tooth OR skin OR bone OR sperm or semen OR tissue OR level* OR concentration* OR ‘time trend’ OR milk OR blood OR ‘whole blood’ OR serum OR plasma OR ‘breast milk’ OR biomarker OR ‘human milk’ OR ‘cord blood’ OR urine OR ‘amniotic fluid’ OR faeces OR placenta OR meconium OR hair OR nail* OR sweat OR saliva OR level* OR concentration* 01 January 2007–31 August 2018 for PFASs other than PFOS and PFOA Data from EFSA CONTAM Panel et al. (2018) Opinion for PFOS and PFOA |
| Occurrence in Food | |
| Search terms Dates | perfluoro* OR pfos OR pfoa OR pfas OR ‘fluorotelomer alcohol’ AND occurrence* OR level* OR concentration* OR amount*OR food OR beverage OR ‘drinking water’ OR ‘bottled water’ OR vegetable* OR legume* OR fruit* OR grain* OR cereal* OR poultry OR chicken OR beef OR turkey OR meat OR egg* OR milk OR seafood OR fish OR shrimp OR prawn* OR mollusc* OR feed OR feedstuff OR beef OR pork OR livestock OR bivalve* 01 January 2007–01 September 2018 |
| Food Processing | |
| Search terms Dates | perfluoro* OR pfos OR pfoa OR pfas OR ‘fluorotelomer alcohol’ AND process* OR cook* OR roast* OR fry* OR boil* OR bak* OR ‘thermal processing’ OR sterilisation OR sterilization OR sterilise OR sterilize OR freez* OR heat* 01 January 2007–01 September 2018 |
| (Dietary) Exposure | |
| Search terms Dates | perfluoro* OR pfos OR pfoa OR pfas OR ‘fluorotelomer alcohol’ AND ‘exposure assessment*’ OR ‘dietary exposure assessment*’ OR ‘human dietary exposure assessment*’ 01 January 2007–01 September 2018 |
| (Non‐dietary) Exposure | |
| Search terms Dates | perfluoro* OR pfos OR pfoa OR pfas OR ‘fluorotelomer alcohol’ AND ‘non‐dietary exposure assessment*’ OR ‘human non‐dietary exposure assessment*’ OR ‘exposure pathway*’ OR ‘indoor exposure’ OR ‘dermal exposure’ OR occupational OR dust OR air OR ‘in‐utero’ OR inutero OR ‘in utero’ OR skin 01 January 2007–31 December 2017 |
| Chemistry and analysis | |
| Search terms Dates | perfluoro* OR pfos OR pfoa OR pfas OR ‘fluorotelomer alcohol’ AND chemistry OR analysis OR determination OR detection OR spectroscopy OR chromatography OR TLC OR GC OR GC‐MS OR HPLC OR LC‐MS OR ICP‐MS 01 January 2007 – 29 June 2016 |
| Production/Use | |
| Search terms Dates | perfluoro* OR pfos OR pfoa OR pfas OR ‘fluorotelomer alcohol’ AND source* OR application OR use* OR production OR ‘production volume’ OR application 01 January 2007–29 June 2016 |
| Environmental fate | |
| Search terms Dates | perfluoro* OR pfos OR pfoa OR pfas OR ‘fluorotelomer alcohol’ AND ‘environmental fate’ OR ‘environmental monitoring’ OR soil OR biosolid OR manure OR sediment OR sewage OR sludge OR water OR ‘waste water*’ OR ‘ground water*’ OR wastewater* OR groundwater* OR river OR land OR lake OR grass OR vegetation 01 January 2007 – 29 June 2016 |