Figure 4.

The distribution of representative targeted genetic alterations between the younger and older patients with lung adenocarcinoma (a) The genetic profiles in different age groups of patients with nonsmall‐cell lung cancer. 246 patients with NSCLC patients were enrolled, and tissue sample were analyzed by NGS assays. (b‐f) The distribution of representative targeted genetic alterations between the younger and older patients. (b) ALK arrangements, (c) BRAF mutations, (d)EGFR mutations, (e) KRAS mutations, (f) MET mutations. Statistical significance was defined as p＜0.05. WT: wide type