Table 1. Patient characteristics and outcomes in younger (<65 years) and older (>=65 years) individuals hospitalized with COVID-19.
ARDS: acute respiratory distress syndrome; BMI: body mass index; COPD: chronic obstructive pulmonary disease; HiO2: high oxygen; IQR: inter-quartile range; COVID, coronavirus disease 2019
Data is presented as number (percentage), except for age and BMI.
| Characteristic | All patients (n=370) | Younger individuals, age<65 (n=132) | Older individuals, age>=65 (n=238) | p-value |
| Demographics | ||||
| Age (years), median (IQR) | 71 (59–82) | 55.5 (47–60) | 79 (72–86) | <.001 |
| Male | 207 (55.9) | 87 (65.9) | 120 (50.4) | .004 |
| Race | ||||
| Whites | 125 (33.8) | 29 (21.9) | 96 (40.3) | <.001 |
| Blacks | 130 (35.1) | 41 (31.1) | 89 (37.4) | .2 |
| Hispanics | 75 (20.3) | 47 (35.6) | 28 (11.8) | <.001 |
| Others | 40 (10.8) | 15 (11.4) | 25 (10.5) | .8 |
| Comorbidities | ||||
| Hypertension | 245 (66.2) | 62 (46.9) | 183 (76.9) | <.001 |
| Diabetes | 157 (42.4) | 52 (39.4) | 105 (44.1) | .4 |
| Cardiac disease | 121 (32.7) | 20 (15.2) | 101 (42.4) | <.001 |
| Chronic kidney disease | 41 (11.1) | 8 (6.1) | 33 (13.9) | .02 |
| COPD | 50 (13.5) | 6 (4.6) | 44 (18.5) | <.001 |
| Malignancy | 72 (19.5) | 13 (9.9) | 59 (24.8) | <.001 |
| BMI (kg/m2), median (IQR) | 27.4 (24–32.1) | 29.4 (25.9–35.5) | 26 (23.1–30) | <.001 |
| Outcomes | ||||
| Severe pneumonia | 239/370 (64.6) | 81/132 (61.4) | 158/238 (66.4) | .3 |
| Severe ARDS | 80/319 (25.1) | 32/125 (25.6) | 48/194 (24.7) | .9 |
| HiO2 requirement | 208/370 (56.2) | 65/132 (49.2) | 143/238 (60.1) | .04 |
| Acute kidney injury | 182/331 (54.9) | 53/120 (44.2) | 129/211 (61.1) | .003 |
| Acute cardiac injury | 112/197 (56.9) | 20/64 (31.3) | 92/133 (69.2) | <.001 |
| Acute liver injury | 74/368 (20.1) | 23/131 (17.6) | 51/237 (21.5) | .4 |
| In-hospital death | 150/365 (41.1) | 27/128 (21.1) | 123/237 (51.9) | <.001 |