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. 2020 Sep 21;40(9):BSR20191571. doi: 10.1042/BSR20191571

Figure 6. PSMA3-AS1 oncogenic activity is in part through negative regulation of miR-302a-3p in vivo.

Figure 6

(A) Distinctive images of tumor formation of xenograft in nude mice from sh-NC, sh-PSMA3-AS1 or sh-PSMA3-AS1+miR-302a-3p inhibitor groups, respectively (n=3 in each group). (B) Tumor volume of mice measured in every 3 days in sh-NC, sh-PSMA3-AS1 or sh-PSMA3-AS1+miR-302a-3p inhibitor groups, respectively. (C) Changes in the tumor weight in nude mice from sh-NC, sh-PSMA3-AS1 or sh-PSMA3-AS1+miR-302a-3p inhibitor groups, respectively (n=3 in each group). (D) Determination of miR-302a-3p expression in xenografts via qRT-PCR. (E,F) The protein and mRNA levels of RAB22A in xenografts. Three independent experiments are carried out. Error bars represent mean ± SD of at least three experiments. *P<0.05; **P<0.01 vs. sh-NC; #P<0.05; ##P<0.01 vs. sh-PSMA3-AS1.