Table 3.

Annualized rates of change in Forced Vital Capacity (liters) and DLco (% predicted) across patients with different grade of involvement of mediastinal lymph nodes on baseline CT scan. LNE- = without mediastinal lymph node enlargement; LNE 1–2 = with 1 or 2 enlarged lymph nodes; LNE ≥ 3 = with 3 or more enlarged lymph nodes. Data are means of predicted values (baseline-12 months) derived from linear mixed models. p Values are for group×time interaction. p Values < 0.05 were considered statistically significant

	12-month mean difference (SE)			p value
	LNE – n = 58	LNE 1–2 n = 63	LNE ≥ 3 n = 31
FVC (liters)	−0.04 (0.073)	−0.095 (0.073)	- 0.178 (0.094)	0.332
DLco (% predicted)	−3.49 (2.35)	- 3.99 (2.12)	- 10.5 (2.55)	0.349