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. 2020 Sep 21;20:286. doi: 10.1186/s12906-020-03074-4

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — The antiviral pneumonia efficacy of XDY in FM1-infected mice. a: Assessment of the appearance and motility changes in the control group, virus group and XDY group at 4 dpi and 7 dpi. b: Body weight changes over 7 days in the control group, virus group and XDY group. *differs significantly (P ≤ 0.05), ** differs significantly(P ≤ 0.01) and ***differs significantly(P ≤ 0.001) when compared with the control group. #differs significantly (P ≤ 0.05), ##differs significantly(P ≤ 0.01) and ###differs significantly (P ≤ 0.001) when compared with the virus group. c. XDY ameliorated the injury of alveolar structure and the infiltration of inflammatory cells compared with that in the virus group as shown by H&E staining of mouse models