Table 1.
OS | PFS | EFS | ||||
---|---|---|---|---|---|---|
Parameters* | HR (95% CI) | p-value | HR (95% CI) | p-value | HR (95% CI) | p-value |
Num. of liver mets | 2.71 (1.44–5.12) | 0.0021** | 2.61 (1.18–5.79) | 0.018 | 2.42 (1.32–4.42) | 0.0042 |
MTV | 2.62 (1.38–4.98) | 0.0034** | 1.96 (0.87–4.41) | 0.11 | 2.29 (1.23–4.24) | 0.0086 |
TLG | 2.62 (1.38–4.98) | 0.0034** | 1.96 (0.87–4.41) | 0.11 | 2.29 (1.23–4.24) | 0.0086 |
SUVpeak | 2.05 (1.09–3.86) | 0.027 | 1.93 (0.86–4.33) | 0.11 | 1.64 (0.90–2.99) | 0.10 |
SUVmean | 1.81 (0.96–3.41) | 0.068 | 0.82 (0.37–1.80) | 0.62 | 1.35 (0.74–2.44) | 0.33 |
SUVmax | 1.48 (0.79–2.77) | 0.22 | 0.83 (0.38–1.82) | 0.64 | 1.16 (0.64–2.09) | 0.63 |
Median thresholds for MTV, TLG, SUVpeak, SUVmean and SUVmax were 9.3mL, 58.3mL, 6.8, 5.3 and 7.8, respectively, arriving at 26 patients in each of the lower and higher risk groups. Number of liver mets was set to =1 vs. >1 arriving at 31 vs. 21 patients in the lower and higher risk groups.
p-values significant after correction for multiple testing (to control for FDR).