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Hazard ratio of globe salvage according to patient characteristics and treatment modalities: (a) including all eyes (unilateral vs. bilateral); (b, c) unilateral and bilateral: based on the International Classification of Retinoblastoma (ICRB). CRD = chemoreduction; IAC = intra-arterial chemotherapy; EBRT = external beam radiation therapy; IVT = intravitreal chemotherapy.
