Table 2.
Treatment modalities and globe salvage rates for intraocular tumor according to International Classification of Retinoblastoma (ICRB).
| Treatment modalities, n = 115 | ICRB group, eyes (globe salvage, %) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| A | B | C | D | E | ||||||
| Unilateral | Bilateral | Unilateral | Bilateral | Unilateral | Bilateral | Unilateral | Bilateral | Unilateral | Bilateral | |
| CRD | — | 4 (100%) | 1 (100%) | 9 (100%) | — | 2 (100%) | — | 9 (66.7%) | 2 (0%) | 19 (47.4%) |
| CRD + plaque | — | — | — | 2 (100%) | 1 (100%) | — | — | — | — | |
| CRD + EBRT | — | — | — | 1 (100%) | — | — | — | 1 (0%) | — | |
| CRD + IAC | — | — | — | 2 (100%) | — | 1 (100%) | 4 (75%) | 4 (100%) | 3 (0%) | 6 (33.3%) |
| CRD + IAC + IVT | — | — | — | 1 (100%) | — | 2 (100%) | 1 (100%) | — | — | |
| CRD + IAC + plaque | — | — | — | — | — | — | 4 (75%) | 1 (0%) | — | |
| CRD + IVT + plaque | — | — | — | 2 (50%) | — | — | — | — | — | |
| CRD + IAC + IVT + plaque | — | — | — | 1 (100%) | — | — | 1 (0%) | — | — | |
| IAC | — | — | — | — | — | — | 1 (0%) | 1 (100%) | 3 (67.7%) | 1 (0%) |
| IAC + IVT | — | — | — | — | — | — | — | — | 1 (100%) | |
| IAC + IVT + plaque | — | — | — | — | — | — | 1 (0%) | — | ||
| Primary enucleation (in our center/from referral hospital) | — | — | — | — | — | — | 2 (1/1) | 1 (0/1) | 7 (7/0) | 13 (8/5) |
| Secondary enucleation (in our center/from referral hospital) | — | — | — | 1 | — | — | 5 (5/0) | 5 (5/0) | 6 (6/0) | 15 (14/1) |
|
| ||||||||||
| Total | 0 | 4 (100%) | 1 (100%) | 18 (94.4%) | 1 (100%) | 5 (100%) | 14 (50%) | 17 (64.7%) | 16 (18.8%) | 39 (28.2%) |
ICRB = International Classification of Retinoblastoma; CRD = chemoreduction; IAC = intra-arterial chemotherapy; EBRT = external beam radiation therapy; IVT = intravitreal chemotherapy.