Table 3.
Treatment modalities for intraocular and extraocular tumors according to the International Retinoblastoma Staging System (IRSS).
| Treatment modalities, n = 124 | IRSS staging, eyes | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 0 | I | II | III | IV | ||||||
| Unilateral | Bilateral | Unilateral | Bilateral | Unilateral | Bilateral | Unilateral | Bilateral | Unilateral | Bilateral | |
| Globe salvage treatment1 | 12 | 48 | — | — | — | — | — | — | — | — |
| CRD + enucleation | — | — | 3 | 15 | — | — | — | — | — | — |
| CRD + IAC + enucleation | — | — | 4 | 4 | — | — | — | — | — | — |
| CRD + EBRT + enucleation | — | — | — | 1 | — | — | 1 | — | 1 | — |
| CRD + IAC + plaque + enucleation | — | — | 1 | 1 | — | — | — | — | — | — |
| CRD + IAC + IVT + plaque + enucleation | — | — | 1 | — | — | — | — | — | — | — |
| CRD + IVT + plaque + enucleation | — | — | — | 1 | — | — | — | — | — | — |
| CRD + exenteration | — | — | 2 | — | — | — | — | — | — | — |
| CRD + exenteration + EBRT | — | — | — | — | — | — | 1 | — | — | — |
| IAC + enucleation | — | — | 2 | 1 | — | — | — | — | — | — |
| IAC + IVT + plaque + enucleation | — | — | 1 | — | — | — | — | — | — | — |
| Primary enucleation (in our center/from referral hospital) | — | — | 9 (8/1) | 14 (8/6) | — | — | — | — | — | 1 (0/1) |
|
| ||||||||||
| Total | 12 | 48 | 23 | 37 | 0 | 0 | 2 | 0 | 1 | 1 |
1Detailed treatment modalities are listed in Table 1. IRSS = International Retinoblastoma Staging System; CRD = chemoreduction; IAC = intra-arterial chemotherapy; EBRT = external beam radiation therapy; IVT = intravitreal chemotherapy.