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. 2020 Jul 30;127(8):997–1022. doi: 10.1161/CIRCRESAHA.120.317295

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© 2020 The Authors.

Circulation Research is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial-NoDerivs License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited, the use is noncommercial, and no modifications or adaptations are made.

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Figure 1. — Proteomic analyses identify global differences in protein abundance and biological processes in aortas of SR-uPA^+/0 and SR-uPA^0/0 mice.

A, Correspondence analysis was applied to 775 proteins identified in extracts of aortas of SR-uPA^+/0 and SR-uPA^0/0 mice. Individual mice of the 2 genotypes are represented by colored spheres. B, Heatmap of 2-dimensional hierarchical cluster analysis for the 100 differentially abundant proteins (false discovery rate [FDR]<0.05). A complete list of these proteins is in Data Set II in the Data Supplement. C, Functional enrichment analysis of the differentially abundant proteins reveals over-represented biological processes. A complete list of these categories is in Data Sets III and IV in the Data Supplement.