TABLE VIII.

Advantages and Disadvantages of Bone Marrow Aspirate Concentrate

Advantages	Disadvantages
Ease of availability	Increased cost and surgical time
Potential for multilineal differentiation (osteoblasts, chondrocytes, lipocytes, tenocytes, etc.)	Need for additional equipment
No risk of malignant transformation	Not osteoconductive
Free of ethical issues	Does not provide structural support
Can be combined with osteoconductive materials (e.g., various bone grafts).	Inherent differences in sample composition among individual patients
Need for additional surgical procedure	The number of osteogenic progenitor cells that are being implanted is unknown at the time of the procedure
Potential for harvest site morbidity